Terminal heart trouble (5)
I believe the answer is:
earth
'terminal' is the definition.
(I've seen this before)
'heart trouble' is the wordplay.
'trouble' is an anagram indicator.
'heart' with letters rearranged gives 'EARTH'.
(Other definitions for earth that I've seen before include "Heart (anag)" , "Land" , "Soil; planet" , "Soil; ground terminal" , "our present abode" .)