Terrible despair across America? Bliss! (8)
I believe the answer is:
paradise
'bliss' is the definition.
(I've seen this before)
'terrible despair across america?' is the wordplay.
'terrible' indicates anagramming the letters.
'across' indicates putting letters inside.
'america?' becomes 'a' (common abbreviation eg in USA).
'despair' is an anagram of 'pardise'.
'pardise' enclosing 'a' is 'PARADISE'.
(Other definitions for paradise that I've seen before include "Idyllic place" , "Garden of Eden" , "Sensual garden" , "a state of bliss" , "limbo" .)