The antithesis of large cold drink (4)
I believe the answer is:
shot
'drink' is the definition.
(I've seen this before)
'the antithesis of large cold' is the wordplay.
I cannot really see how this works, but
'the' could be 't' (the is pronounced as a 't' sound in some dialects) and 't' is present in the answer.
'of' could be 'o' and 'o' is found within the answer.
The remaining letters 'sh' is a valid word which might be clued in a way I don't understand.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for shot that I've seen before include "Gunned down - go - guess" , "Slug" , "description of some silk" , "Small drink; photograph" , "Attempt - hit with bullet" .)