The Biggest Little City in the World? (4)
I believe the answer is:
reno
'the biggest little city in the world' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for reno that I've seen before include "Nevada gambling resort" , "City in Nevada known for casinos and easy divorces" , "Nevada marriage and divorce centre" , "Divorce capital of Nevada" , "Nevadan city" .)