The chap appears after analgesic gutted pain (4)
I believe the answer is:
ache
'pain' is the definition.
(ache is a kind of pain)
'the chap appears after analgesic gutted' is the wordplay.
'the chap' becomes 'he' (**).
'appears after' says to put letters next to each other.
'gutted' means to remove the middle letters (to gut something is to remove its insides).
'analgesic' with its centre taken out is 'ac'.
'he' after 'ac' is 'ACHE'.
(Other definitions for ache that I've seen before include "Dull throbbing pain" , "Feel sore" , "Longing" , "Suffer dull pain" , "suffering" .)