The fate of Desmond Little (7)
I believe the answer is:
destiny
'the fate' is the definition.
(synonyms)
'desmond little' is the wordplay.
'desmond' becomes 'des' (I've seen this in other clues).
'little' becomes 'tiny' (similar in meaning).
'des'+'tiny'='DESTINY'
'of' is the link.
(Other definitions for destiny that I've seen before include "portion" , "Ultimate fate" , "The future as arranged by fate" , "Kismet, fate" , "must?" .)