The female subsequently lacking a sanctuary (7)
I believe the answer is:
shelter
'sanctuary' is the definition.
(thesaurus)
'the female subsequently lacking a' is the wordplay.
'the female' becomes 'she' (I've seen this before).
'subsequently' becomes 'later' (I've seen this before).
'lacking' suggests deleting specific letters.
'later' with 'a' taken out is 'lter'.
'she'+'lter'='SHELTER'
(Other definitions for shelter that I've seen before include "Cover, protection" , "Sanctuary, protection" , "Shield as from rain" , "Place of refuge" , "'Refuge, cover (7)'" .)