The lager to change to on the whole (10)
I believe the answer is:
altogether
'on the whole' is the definition.
(synonyms)
'the lager to change' is the wordplay.
'change' indicates an anagram.
'the'+'lager'+'to'='thelagerto'
'thelagerto' with letters rearranged gives 'ALTOGETHER'.
'to' acts as a link.
(Other definitions for altogether that I've seen before include "Wholly" , "nude in this" , "totally" , "Quite" , "Completely, on the whole" .)