The largest city in Syria (6)
I believe the answer is:
aleppo
'the largest city in syria' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for aleppo that I've seen before include "Largest city in Syria before the massive damage of the civil war" , "Lap Poe around the Syrian city" , "Ancient city, in Syria" , "Foreign city" , "Tomorrow" .)