The latest from her: city keeping up rise of large lorries (8)
I believe the answer is:
newsgirl
'the latest from her' is the definition.
(source of the latest news)
'city keeping up rise of large lorries' is the wordplay.
'city keeping' becomes 'wen' (I can't explain this - if you can you should give a lot more credence to this answer).
'up' is a reversal indicator (in down clue: letters go upwards).
'rise of' says the letters should be written backwards.
'large' becomes 'l'.
'lorries' becomes 'rigs' (rig can mean a truck or lorry).
'wen' backwards is 'new'.
'l'+'rigs'='lrigs'
'lrigs' reversed gives 'sgirl'.
'new'+'sgirl'='NEWSGIRL'
(Other definitions for newsgirl that I've seen before include "Female delivering papers" , "rag doll" .)