The least we lost? (6)
I believe the answer is:
lowest
'the least' is the definition.
(thesaurus)
'we lost?' is the wordplay.
'we lost' anagrams to 'LOWEST'.
But, I'm not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for lowest that I've seen before include "Owlets at the bottom level" , "Nearest the ground" , "Given maximum reduction" , "Nadir" , "Smallest number" .)