The man caught twitching, agitated (6)
I believe the answer is:
hectic
'agitated' is the definition.
('hectic' can be similar in meaning to 'agitated')
'the man caught twitching' is the wordplay.
'the man' becomes 'he'.
'caught' becomes 'c' (cricket abbreviation).
'twitching' becomes 'tic' (tic is a kind of twitching).
'he'+'c'+'tic'='HECTIC'
(Other definitions for hectic that I've seen before include "Frantic, busy" , "Involving feverish activity, flushed" , "'Rushed, madly busy (6)'" , "Bustling" , "'Excited, flustered or rushed (6)'" .)