The mixture, shaken, is nice. I'd swallowed it myself (8)
I believe the answer is:
medicine
'the mixture' is the definition.
(thesaurus)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for medicine that I've seen before include "Curative drug" , "Profession of a physician" , "The discipline of diagnosis and treatment of disease" , "Remedy for illness" , "Laughter is said to be the best one" .)