The —, one of three ships commanded by Christopher Columbus in 1492 (4)
I believe the answer is:
nina
(Other definitions for nina that I've seen before include "Al Hirschfeld's 'hidden' daughter" , "hidden crossword message" , "Girl" , "- - Simone, 1933-2003, singer" , "One of Columbus's ships in 1492; girl's name" .)