The only one afoot? (4)
I believe the answer is:
sole
'the only one' is the definition.
(I've seen this in another clue)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for sole that I've seen before include "Shoe part -- lone" , "European flatfish" , "Underside of the foot" , "A lonely sort of flatfish" , "fish in the sea!" .)