The sign of a drama centre? (3)
I believe the answer is:
ram
'the sign' is the definition.
(Aries the Ram, sign of the zodiac)
'of a drama centre?' is the wordplay.
'of' indicates a hidden word.
'RAM' is hidden within 'drama centre'.
(Other definitions for ram that I've seen before include "Tup" , "Temporary computer memory, initially" , "force" , "Male sheep - bash into it" , "Animal to batter" .)