The sky pilot's home again (5)
I believe the answer is:
padre
'the sky pilot's' is the definition.
('padre' can be a synonym of 'sky pilot')
'home again' is the wordplay.
'home' becomes 'pad' (I've seen this before).
'again' becomes 're'.
'pad'+'re'='PADRE'
(Other definitions for padre that I've seen before include "Minister" , "Chaplain to armed forces" , "Cleric" , "Man of god - drape (anag)" , "Services' chaplain" .)