The trouble is me, it might be said! (3)
I believe the answer is:
woe
'the trouble' is the definition.
(I've seen this before)
'me it might be said' is the wordplay.
I cannot really see how this works, but
'it' could be 'e' ('e' can mean 'electronic' which is similar to 'IT') and 'e' is found within the answer.
The remaining letters 'wo' is a valid word which might be clued in a way I don't see.
This may be the basis of clue (or it may be nonsense).
'is' acts as a link.
Can you help me to learn more?
(Other definitions for woe that I've seen before include "'Wednesday's child is full of ...'" , "Misery, great suffering" , "Misery - tribulation" , "Grief, misery" , "Misfortune" .)