The two signs of hesitation seen in troubles (7)
I believe the answer is:
bothers
'troubles' is the definition.
(I know this)
'the two signs of hesitation seen in' is the wordplay.
'the two' becomes 'both' (synonyms).
'signs of' becomes 's' (I can't justify this - if you can you should give a lot more credence to this answer).
'hesitation' becomes 'er' (sound made while hesitating - um, er).
'seen in' indicates putting letters inside.
'both'+'s'='boths'
'boths' placed around 'er' is 'BOTHERS'.
Can you help me to learn more?
(Other definitions for bothers that I've seen before include "Troubles" , "Upsets" .)