The whole network is with one again (6)
I believe the answer is:
entire
'the whole' is the definition.
(thesaurus)
'network is with one again' is the wordplay.
'network' becomes 'ent' (I can't explain this - if you can you should give a lot more credence to this answer).
'is with' means one lot of letters go next to another.
'one' becomes 'i' (Roman numeral).
'again' becomes 're'.
'ent'+'i'+'re'='ENTIRE'
Can you help me to learn more?
(Other definitions for entire that I've seen before include "Whole; absolute" , "outright" , "Envelope" , "Unharmed - total" , "Full, intact" .)