The whole ten are mad with anger (6)
I believe the answer is:
entire
'the whole' is the definition.
(I've seen this before)
'ten are mad with anger' is the wordplay.
'are mad' indicates anagramming the letters.
'with' says to put letters next to each other.
'anger' becomes 'ire' (synonyms).
'ten' is an anagram of 'ent'.
'ent'+'ire'='ENTIRE'
(Other definitions for entire that I've seen before include "in one piece" , "porter" , "Full and complete" , "Whole and complete" , "Whole - undamaged" .)