Theatre individuals twice interrupted by singular replies (9)
I believe the answer is:
responses
'replies' is the definition.
('response' can be a synonym of 'reply')
'theatre individuals twice interrupted by singular' is the wordplay.
I cannot quite see how this works, but
'singular' could be 's' (abbreviation sometimes used in dictionaries) and 's' is present in the answer.
'theatre' could be 'rep' (I've seen this before) and 'rep' is found within the remaining letters.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for responses that I've seen before include "Answers" , "feedback!" .)