There's no end of comfort in amphibian's intelligence (4)
I believe the answer is:
news
'intelligence' is the definition.
(I know that intelligence can be written as news)
'there's no end of comfort in amphibian's' is the wordplay.
'there's' says to put letters next to each other.
'no' becomes 'n' (common abbreviation y/n).
'end of comfort in amphibian' becomes 'ews' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'n'+'ews' is 'NEWS'.
Can you help me to learn more?
(Other definitions for news that I've seen before include "Fresh tidings" , "Latest information" , "This is compiled for one" , "that's aired at six o'clock" , "Important information" .)