They can look to give noted encouragement (4)
I believe the answer is:
eyes
'they' is the definition.
Both the definition and answer are plural nouns.
Perhaps there's an association between them I don't understand?
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for eyes that I've seen before include "Storm centres" , "Globular organs" , "Regards -- features of a potato" , "Blemishes on potatoes" , "They're said to be the mirrors of the soul" .)