They don’t agree with new ones (4)
I believe the answer is:
noes
'they don't agree' is the definition.
The definition suggests an adverb but the answer is not.
'new ones' is the wordplay.
'new' indicates an anagram.
'ones' with letters rearranged gives 'NOES'.
'with' is the link.
Can you help me to learn more?
(Other definitions for noes that I've seen before include "People voting against something" , "Negative votes as at committee meetings" , "they are dissenting" , "negative responses" , "more than one refusal" .)