They go through space to Saturn as a change (10)

I believe the answer is:

astronauts

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'they go through space' is the definition.
The definition suggests an adverb but the answer is not.

'to saturn as a change' is the wordplay.
'a change' indicates an anagram.
'to'+'saturn'+'as'='tosaturnas'
'tosaturnas' anagrammed gives 'ASTRONAUTS'.

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(Other definitions for astronauts that I've seen before include "Space voyagers" , "Spacemen" , "high fliers" , "long-distance travellers" .)

I've seen this clue in The Globe and Mail.

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