They make fast canal transport possible (5)
I believe the answer is:
locks
'they' is the definition.
Both the answer and definition are plural nouns.
Perhaps you can see an association between them that I don't see?
I don't understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for locks that I've seen before include "Tresses" , "Clusters of hair" , "Securely fixes" , "Canal features" , "Door fasteners" .)