Thick English lot (4)
I believe the answer is:
fate
'lot' is the definition.
('fate' can be a synonym of 'lot')
'thick english' is the wordplay.
'thick' becomes 'fat' ('fat' can be similar in meaning to 'thick').
'english' becomes 'e' (abbreviation).
'fat'+'e'='FATE'
(Other definitions for fate that I've seen before include "Predetermined end" , "E.g. Clotho, Atropos" , "Destiny, kismet" , "Predestiny" , "Lot -- doom" .)