Thorn in your side (4)
I believe the answer is:
bane
(Other definitions for bane that I've seen before include "Curse" , "it causes misery" , "Cause of distress, ruin" , "scourge" , "Cause of great distress in a bean" .)
I believe the answer is:
bane
(Other definitions for bane that I've seen before include "Curse" , "it causes misery" , "Cause of distress, ruin" , "scourge" , "Cause of great distress in a bean" .)