Crossword Genius

Those up with the locals? (4,3,4)

Ross

I believe the answer is:

town and gown

I'm a little stuck... Click here to teach me more about this clue!

'the locals?' is the definition.
I know nothing about this answer so I cannot judge whether it can be defined by this definition.

'those up with' is the wordplay.
I cannot quite see how this works, but
'with' could be 'and' (I've seen this before) and 'and' is found within the answer.
This may be the basis of clue (or it may be nonsense).

Can you help me to learn more?

I've seen this clue in The Independent.
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