Those wanted are dead? It's uncertain (10)
I believe the answer is:
desiderata
'those wanted' is the definition.
(list of things which are desired)
'are dead? it's uncertain' is the wordplay.
'uncertain' is an anagram indicator.
'are'+'dead'+'its'='aredeadits'
'aredeadits' with letters rearranged gives 'DESIDERATA'.
(Other definitions for desiderata that I've seen before include "list of wants" , "what are needed" , "much-needed items" , "Wanted things" .)