Though false, they possibly have value in Isleworth (4)
I believe the answer is:
lies
'though false they' is the definition.
The definition suggests a plural noun which matches the answer.
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for lies that I've seen before include "Perversions of the truth" , "Untruths" , "Wallows" , "False statements" , "pork pies" .)