Three-headed dog of Greek mythology — cubes err (anag) (8)
I believe the answer is:
cerberus
(Other definitions for cerberus that I've seen before include "Three-headed watchdog that guarded Hades" , "underworld guard" , "Three-headed dog guarding entrance to Hades" , "Three-headed guard dog" , "Three-headed watchdog guarding entrance to Hades" .)