Throttle great to adjust (7)
I believe the answer is:
garotte
'throttle' is the definition.
(I know that garotte is a more specific form of the action the throttle)
'great to adjust' is the wordplay.
'adjust' indicates anagramming the letters.
'great'+'to'='greatto'
'greatto' with letters rearranged gives 'GAROTTE'.
(Other definitions for garotte that I've seen before include "Kill by strangulation" , "Strangle" , "Facility to dispose of person" , "Spanish method of execution" , "throttle" .)