Ties off the location (4)
I believe the answer is:
site
'the location' is the definition.
(site is a kind of location)
'ties off' is the wordplay.
'off' is an anagram indicator.
'ties' anagrammed gives 'SITE'.
(Other definitions for site that I've seen before include "setting" , "Building plot" , "Building land" , "Where something is located" , "internet location" .)