Ties up location (4)
I believe the answer is:
site
'location' is the definition.
(site is a kind of location)
'ties up' is the wordplay.
'up' indicates an anagram (letters get chucked up).
'ties' is an anagram of 'SITE'.
(Other definitions for site that I've seen before include "Situation (of a building)" , "Area set aside for building" , "Location (of building, dig etc)" , "setting" , "Locale" .)