Time to change article (4)
I believe the answer is:
item
'article' is the definition.
(both can mean an object or thing)
'time to change' is the wordplay.
'to change' indicates an anagram.
'time' with letters rearranged gives 'ITEM'.
(Other definitions for item that I've seen before include "Piece of news: unit" , "Individual thing" , "Object in a list" , "Individual article or unit" , "One of a series (or a couple!)" .)