Time to change something (4)
I believe the answer is:
item
'something' is the definition.
(item means a thing)
'time to change' is the wordplay.
'to change' is an anagram indicator.
'time' is an anagram of 'ITEM'.
(Other definitions for item that I've seen before include "Two people romantically linked" , "A thing or unit" , "couple making out {TIME}..." , "One of a series (or a couple!)" , "Single article on a list" .)