Times numbers around average? Not at all! (2,2,5)
I believe the answer is:
by no means
'not at all' is the definition.
(both can mean to no extent or in no way)
'times numbers around average?' is the wordplay.
I cannot quite see how this works, but
'times' could be 'by' (both can mean 'multiplied by') and 'by' is present in the answer.
'around' could be 'o' (I've seen this in other clues) and 'o' is located in the answer.
'average?' could be 'mean' (type of average) and 'mean' is present in the answer.
This explanation may well be incorrect...
(Other definitions for by no means that I've seen before include "Definitely not" , "Without using any method" , "Certainly not, not in any way" , "Certainly not, perish the thought" , "Forbids" .)