Tire of Italian river on self-reflection (4)
I believe the answer is:
poop
'tire' is the definition.
(I've seen this in another clue)
'of italian river on self-reflection' is the wordplay.
'of' becomes 'o''.
'italian river' becomes 'po' (river in Italy).
'on' says to put letters next to each other.
'self reflection' becomes 'p' (I can't justify this - if you can you should give a lot more credence to this answer).
'o' put after 'po' is 'poo'.
'poo'+'p'='POOP'
Can you help me to learn more?
(Other definitions for poop that I've seen before include "Highest aftmost deck" , "High deck at old sailing ship's stern" , "Deck at stern of ship" , "Tony" , "Whichever way you see them, the facts" .)