Tired clothes ending in laundry (5)
I believe the answer is:
weary
'tired' is the definition.
('weary' can be similar in meaning to 'tired')
'clothes ending in laundry' is the wordplay.
'clothes' becomes 'wear' ('wear' can be a synonym of 'clothes').
'ending in' says to take the final letters.
The final letter of 'laundry' is 'y'.
'wear'+'y'='WEARY'
(Other definitions for weary that I've seen before include "Enervated" , "Tired - bored" , "spent" , "Worn-out" , "Physically and mentally fatigued" .)