Tired of holding a novice to be clever! (5)
I believe the answer is:
slick
'be clever' is the definition.
(I've seen this in another clue)
'tired of holding a novice' is the wordplay.
'tired of' becomes 'sick' (I can't justify this - if you can you should give a lot more credence to this answer).
'holding' indicates putting letters inside.
'a novice' becomes 'L' (as in a learner driver with L-plates on their car).
'sick' enclosing 'l' is 'SLICK'.
'to' acts as a link.
Can you help me to learn more?
(Other definitions for slick that I've seen before include "Glibly assured" , "Film of spilled oil" , "Smooth" , "Showing Polish" , "it's very oily" .)