Titanic victim men sedated, to an extent (7)
I believe the answer is:
immense
'titanic' is the definition.
(thesaurus)
'victim men sedated to an extent' is the wordplay.
'to an extent' indicates the answer is hidden within the clue.
'IMMENSE' can be found hidden inside 'victim men sedated'.
(Other definitions for immense that I've seen before include "Superb" , "'Gigantic, extensive (7)'" , "Exceedingly large" , "Massive" , "Unusually large or great" .)