Crossword Genius

Titans of business defeat US Feds, ignoring the odds (10)

Ross

I believe the answer is:

colossuses

'titans' is the definition.

'business defeat us feds ignoring the odds' is the wordplay.
'business' becomes 'co'.
'defeat' becomes 'loss' (I've seen this before).
'ignoring the odds' indicates alternate letters (letters in odd-numbered positions are removed).
The alternate letters of 'feds' are 'es'.
'co'+'loss'+'us'+'es'='COLOSSUSES'

'of' is the link.

I've seen this clue in The Guardian.
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