Title left with nothing at home wanting cut of beef (7)
I believe the answer is:
sirloin
'cut of beef' is the definition.
(I've seen this before)
'title left with nothing at home' is the wordplay.
'title' becomes 'sir' (respectful address for a man).
'left' becomes 'l' (common abbreviation).
'with' says to put letters next to each other.
'nothing' becomes 'O' (O resembles 0).
'at home' becomes 'in' ('I'm in' can mean 'I'm at home').
'sir'+'l'+'o'+'in'='SIRLOIN'
'wanting' is the link.
(Other definitions for sirloin that I've seen before include "Type of steak" , "Upper part of loin of beef" , "Good cut of beef" , "Prime cut of beef" , "(Knighted?) cut of meat" .)