To begin with, a masterful artist tries instrument made by renowned violin-making family (5)
I believe the answer is:
amati
'renowned violin-making family' is the definition.
(I've seen this before)
'to begin with a masterful artist tries instrument' is the wordplay.
'to' becomes 'a' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'begin with' suggests taking the first letters.
The first letters of 'masterful artist tries instrument' is 'mati'.
'a'+'mati'='AMATI'
'made by' acts as a link.
Can you help me to learn more?
(Other definitions for amati that I've seen before include "Famous violin maker" , "Noted violin maker" , "Noted Cremona violinmaking family" , "A violinist" , "One's played" .)