Toe swelling (6)
I believe the answer is:
bunion
'toe swelling' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for bunion that I've seen before include "Something painful" , "Painful swelling at base of big toe" , "Foot fault" , "Swelling on the foot" , "Swelling at base of toe with thickened skin" .)