Toss out the drunks! (4)
I believe the answer is:
sots
'the drunks' is the definition.
('sot' can be a synonym of 'drunk')
'toss out' is the wordplay.
'out' indicates anagramming the letters (out can mean wrong or inaccurate).
'toss' anagrammed gives 'SOTS'.
(Other definitions for sots that I've seen before include "Drunks" , "Boozers" , "Chronic drinkers" , "Sponges" , "Habitual drunkards" .)