Tossing and turning irately, European heard wake-up call (7,5)
I believe the answer is:
reality check
'wake-up call' is the definition.
(I've seen this in another clue)
'tossing and turning irately european heard' is the wordplay.
'tossing and turning' indicates an anagram.
'european' becomes 'Czech ' (Czech is an example).
'heard' indicates a 'sounds like' (homophone) clue.
'czech' is a homophone of 'check'.
'irately' is an anagram of 'reality'.
'reality'+'check'='REALITY CHECK'
(Other definitions for reality check that I've seen before include "Sobering fact" , "In which one is reminded of things as they are" , "Reminder of the true state of affairs" , "Reminder of true conditions" , "Moment to consider things in an honest manner" .)