Total fury supporting hospital department (6)
I believe the answer is:
entire
'total' is the definition.
(I know that total can be written as entire)
'fury supporting hospital department' is the wordplay.
'fury' becomes 'ire' (ire is intense rage).
'supporting' means one lot of letters go next to another (in a down clue, some letters go below others).
'hospital department' becomes 'ENT' (Ear, Nose and Throat department).
'ire' put after 'ent' is 'ENTIRE'.
(Other definitions for entire that I've seen before include "With no part left out" , "excluding nothing" , "Unharmed - total" , "Full, intact" , "Utter" .)